Henochschonlein purpura hsp is a condition that causes your immune system to attack and damage your blood vessels. The most severe complication of this condition is kidney damage, which can cause blood in the urine, swelling, and high blood pressure. Henochschonlein purpura on an infants legs illustration henochschonlein purpura is more commonly seen in children than adults and often occurs after an upper respiratory infection. Henochschonlein purpura is a systemic vasculitis mediated by ig a. It gets its name from two german doctors, johann schonlein and eduard henoch, who. In most cases, the diagnosis of hsp can be made by clinical findings. Henochschonlein purpura also known as anaphylactoid purpura is a type of vasculitis that affects small blood vessels and characterized by elevated immunoglobulin a iga. Hsp can happen at any age but is most common in children 2 to 11 years of age.
The streptococcal igabinding peptides sap, designated sap4, sap22, and. A smallvessel vasculitis mediated by immunoglobulin ig acontaining immune complexes and char. Henochschonlein purpura hsp is an immunologically mediated disease associating purpura plus urticaria, characteristically affecting lower limbs, buttocks, and elbows. The patient in this video presented to the emergency department with henochschonlein purpura hsp and his mother, a cnra, agreed to allow us to demonstrate his rash and discuss this. Highdose methylprednisolone pulse therapy for treatment. Henochschonlein purpura, also called igavasculitis, is a systemic small vessels vasculitis with immunoglobulin a1dominant immune deposits. Henochschonlein purpura pointofcare quick reference. Iga nephropathy igan and henochschonlein purpura hsp are diseases.
Henochschonlein purpura hsp, also called immunoglobulin a vasculitis. Neurologic manifestations of schonlein henoch purpura. Henoch schonlein purpura hsp is a condition that causes your immune system to attack and damage your blood vessels. The history of henoch schonlein started with dr william heberden, a london physician, described the first cases of henoch schonlein hee. Henochschonlein purpura synonyms, henochschonlein purpura pronunciation, henochschonlein purpura translation, english dictionary definition of henochschonlein purpura.
Schoenlein henoch purpura shp may show a cohort of symptoms such as. Henoch schonlein history henoch schonlein purpura support. National high blood pressure education program working group on high blood. Hsp is the most common vasculitis in children, with an incidence of about. Hsp most commonly affects the blood vessels in your skin, joints, intestines, and kidneys. Henochschonlein purpura hsp is a disease that causes small blood vessels to become inflamed and leak blood. Hsp presents with purple spots on the skin purpura, arthralgia, digestive problems, and kidney injury.
Henochschonlein purpura hsp is an immunemediated vasculitis. National institutes of health, through the national library of medicine, developed clinicaltrials. The tetrad of purpura, arthritis, kidney inflammation, and abdominal pain is often. Manejo del sindrome uremicohemolitico hospital garrahan. Henochschonlein purpura hsp is an acute immunoglobulin a igamediated disorder characterized by a generalized vasculitis involving.
Damage to your blood vessels causes them to swell and bleed. Purpura not due to a low platelet count, caused by inflammation in blood vessels of the skin, is the hallmark of hsp. Henochschonlein purpura hsp, also called immunoglobulin a vasculitis igav, is a vascular disease that primarily affects small blood vessels. Its not usually serious, but can sometimes lead to kidney problems.
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